Statin drugs (also called HMG-CoA reductase inhibitors) have been shown to deplete the body’s stores of CoQ10, even beyond age-related declines.
Clinical trials have shown that patients being treated for elevated cholesterol with statin medications are actually at increased risk for cardiovascular problems, such as heart failure.
This is because statin drugs not only block production of cholesterol, they also block CoQ10 production—and CoQ10 is needed for a healthy heart. Myalgia (muscle pain) and liver damage have also been reported following statin drug use.
Those on statin medications should consult their physician. They may benefit from supplementing with 100 to 400 mg of CoQ10 per day. There is no known negative interaction; in fact, supplemental CoQ10 may reverse statin drug-induced myalgia and heart muscle weakness.
Supplemental CoQ10 has not been shown to reduce statins’ cholesterol-lowering properties or to have any adverse reaction related to statin use.
Ghirlanda, G., et al. (1993). Evidence of plasma CoQ10-lowering effect by HMG-CoA reductase inhibitors: a double-blind, placebo-controlled study, Journal of Clinical Pharmacology, 33:226-229.
Rundek, T. et al. (2004, June). Atorvastatin decreases the coenzyme Q10 level in the blood of patients at risk for cardiovascular disease and stroke. Archives in Neurology, Vol 61, 889-892.
Langsjoen, P.H. & Langsjoen, A.M. (1999). Overview of the use of CoQ10 in cardiovascular disease. BioFactors, 9(2-4):237-284.
Langsjoen, P.H.& Langsjoen, A.M. (1998). Review of Coenzyme Q10 in cardiovascular disease with emphasis on heart failure and ischemic reperfusion. Asia Pacific Heart Journal, 7(3):160-168.
Coenzyme Q10 (bacteria or yeast)......................100 mg
Rice bran oil, softgel capsule (gelatin, glycerin, purified water, carob), natural tocopherols.
Coenzyme Q10 is used to help support and maintain cardiovascular health.
Consult a physician prior to use if you are pregnant or breastfeeding or if you are taking blood pressure medication.
Keep out of reach of children.
Contains no artificial colours, preservatives or sweeteners; dairy, starch or wheat.