Melatonin is an important neurohormone that regulates the sleep–wake cycle. Disturbances in melatonin levels are often associated with jet lag, shift work, and stress. Natural melatonin synthesis also declines with age. Supplemental melatonin helps support restful, restorative sleep for adults suffering from sleep restrictions or altered sleep schedules, like shift work and jet lag, and provides all the benefits associated with a good night’s rest.