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The Ultimate Guide to CoQ10
CoQ10 plays a vital role in your health. As a naturally produced nutrient, it is best known for cell growth and maintenance. As you age, CoQ10 levels decrease, therefore supplementation is often recommended. In the Ultimate Guide to CoQ10, you can learn about the role it plays in your body, and how to choose the right product for your specific needs.
Improve Your Energy with CoQ10
Coenzyme Q10, also known as CoQ10 or ubiquinone, is a natural antioxidant that is produced within every cell of the body. It has a critical role in energy production within the mitochondria, the energy-producing structure in cells. Cellular energy is made in the form of ATP (adenosine triphosphate), which is needed for the healthy function of all organs and systems in the body, especially heart health.
Key facts about CoQ10:
• Supports cardiovascular health
• Reduces the frequency of migraine headaches when taken as a prophylactic/preventative
• Provides antioxidant protection against oxidative stress
• Restores CoQ10 levels that decline due to deficiencies caused by statin drugs
• Replenishes CoQ10 levels that naturally decline with age
CoQ10 works at a cellular level
CoQ10 is an antioxidant that occurs naturally within the body’s cells. Its main role is to kick-start cellular energy production and provide antioxidant protection. These are needed for the proper function of every organ and system within the body. Organs with high energy demands, include the heart, liver, kidneys, and pancreas.
Although CoQ10 is produced by the body, levels decline naturally with age during adulthood. They are also depleted by statin drugs and high levels of oxidative stress. When levels decline, it lowers the body’s ability to draw energy from food, putting strain on the heart, nerves, muscles, immune system, and the body’s various functions. A person may need different amounts of CoQ10 depending on their state of health, age, and lifestyle to help support cardiovascular health and cellular energy production.
What is cellular energy?
Just like it sounds, cellular energy is the energy produced within cells. Nutrients from the food that you eat are converted within each cell’s mitochondria into ATP (adenosine triphosphate). This is the form of energy that drives most processes within the body, from heart contractions to nerve impulses.
Feel energetic in the garden
Enjoy the whole day, out on the road with an old friend
Work those new jogging shoes in
Benefits of CoQ10
Supplementing your diet with CoQ10, especially as you age, can help maintain healthy nerves, muscles and cells, as well as a healthy heart. Three of its main benefits are:
CoQ10 provides antioxidant protection and is a key nutrient for preventing free radicals from causing oxidative damage to the body.
What is an antioxidant?
Antioxidants are compounds found in natural foods, such as fresh fruits and vegetables, green tea, as well as herbs and spices. They prevent or slow oxidation of the body’s cells, including those of proteins, DNA, and fats. Similar to the action of rust on metal, oxidation in the body damages cells and tissues, and is believed to drive the aging process.
Free radical defense
Eating the recommended number of servings of fruits and vegetables each day, in addition to taking CoQ10, helps supply the antioxidants that the body needs to neutralize free radicals. These are highly unstable molecules formed as a by-product of normal metabolism, and from disease, strenuous physical activity, and pollution. Taking a CoQ10 supplement will help replenish cellular levels for better antioxidant support and maintenance of good health.
CoQ10 supports a healthy cardiovascular system in different ways:
- As an antioxidant, CoQ10 helps fight oxidative stress and lowers blood pressure. This is a big factor in cardiovascular disease, because oxidative stress can cause problems in the heart and blood vessels.
- The heart is a muscle and it relies on a good supply of CoQ10 for making the ATP that fuels heart contractions. When levels decline, it puts stress on the heart and limits its ability to circulate blood effectively.4
- Helps reduce the frequency of migraine headaches, including those with aura
- Reduces the nausea and vomiting that sometimes occurs with migraines
- Replenishes CoQ10 levels to help fight the oxidative stress caused by migraines
What Causes CoQ10 to Decline?
Although CoQ10 is made by the body, levels decline naturally with age during adulthood.4 Few foods are reliable sources of CoQ10 and its absorption from food is often poor because it will not mix with water. Supplementation is the most-effective way to replenish the body’s levels.
The more oxidative stress you experience, the higher your demands for CoQ10. This is an important consideration for people with high oxidative stress levels, such as endurance athletes, smokers, or anyone recovering from disease. When not replenished, a higher demand for CoQ10 can exhaust the body’s natural levels, leading to fatigue and free radical damage to muscles.1
Statins, also called HMG-CoA reductase inhibitors, are a group of prescription drugs used to reduce high-cholesterol levels in the blood. Statins, and some other medications, interact with the body’s natural production of CoQ10. Although statins are an effective medicine, using them for long periods lowers the natural levels of CoQ10 in the body. This may have side effects on the muscles and liver. Common muscle symptoms include:
Taking supplemental CoQ10 with statin therapy is recommended for maintaining healthy levels of CoQ10 in the body and possibly reducing the risk of side effects.9
Choose a CoQ10 Product that’s Right for You
CoQ10 can be taken on its own or combined with other heart-healthy ingredients, such as omega-3 fatty acids and plant sterols. Webber Naturals offers products that provide low daily doses, anywhere from 30–60 mg per day, along with higher strengths that range from 100–400 mg per day. Choosing the best CoQ10 formula for your needs will depend on your state of health, age, and lifestyle factors. If you use blood-thinning medications or other drugs, discuss CoQ10 with your physician prior to use.
CoQ10 supplementation is something that all adults over the age of 40 should consider for improving overall health and energy levels as they age. It may also be considered by individuals with high cholesterol who are on statin therapy or with a family history of cardiovascular disease, as well as migraine headache sufferers.
The CoQ10 product line from Webber Naturals offers high-quality supplements for cellular health and cardiovascular support.
An enhanced absorption formula.
This is a great choice for seniors or anyone taking statin medication or beta-blockers who need a product that is easier to absorb and produces a higher concentration of CoQ10 in the blood.
Combines the heart health benefits of CoQ10 with the omega-3 fatty acids EPA and DHA. CoQ10 supports cardiovascular health and helps reduce the frequency of migraine headaches, while the omega-3s also help lower serum triglycerides/triacylglycerol levels.
Provides well-rounded cardiovascular support with a combination of CoQ10, EPA, DHA, and plant sterols. This product is useful for helping reduce blood total and LDL cholesterol, and lowering serum triglycerides.
The Heart and Stroke Foundation does not endorse any Webber Naturals products and does not make any claims about their efficacy or health benefits. The Heart and Stroke Foundation is a recipient of sponsorship money raised through the sale of these Webber Naturals products.
™The heart and / Icon and the Heart & Stroke and Heart Smart word marks are trademarks of the Heart and Stroke Foundation of Canada used under license.
Proceeds from the sale of Webber Naturals products will go towards supporting the Heart and Stroke Foundation in 2019 and 2020 to a maximum of $120,000.
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1. Niklowitz P, Fischer A, Onur S, et al. Smoking habits and coenzyme Q10 status in healthy European adults. Arch Med Sci. 2016; 12(4):715-20.
2. Liguori I, Russo G, Curcio F, et al. Oxidative stress, aging, and disease. Clin Interv Aging. 2018; 13:757-72.
3. Bhagavan HN & Chopra RK. Plasma coenzyme Q10 response to oral ingestion of coenzyme Q10 formulations. Mitochondrion. 2007; 7:S78-88.
4. Garrido-Maraver J, Cordero MD, Oropesa-Avila M, et al. Coenzyme Q10 therapy. Mol Syndromol. 2014; 5(3-4):187-97.
5. Hershey AD, Powers SW, Vockell AL, et al. (Coenzyme Q10 deficiency and response to supplementation in pediatric and adolescent migraine. Headache. 2007; 47(1):73-80.
6. Sandor PS, Di Clemente L, Coppola G, et al. Efficacy of coenzyme Q10 in migraine prophylaxis: a randomized controlled trial. Neurology. 2005; 64(4):713-715.
7. Rozen TD, Oshinsky ML, Gebeline CA, et al. Open label trial of coenzyme Q10 as a migraine preventative. Cephalgia. 2002; 22(2):137-141.
8. Ochiai A, Itagaki S, Kurokawa T, et al. Improvement in intestinal coenzyme q10 absorption by food intake. Yakugaku Zasshi. 2007; 127(8):1251-4.
9. Skarlovnik A, Janic M, Lunder M, et al. Coenzyme Q10 supplementation decreases statin-related mild-to-moderate muscle symptoms: a randomized clinical study. Med Sci Monit. 2014; 6(20):2183-8.
10. Ramachandran R. & Wierzbicki AS. Statins, muscle disease and mitochondria. J Clin Med. 2017; 6(8):E75.
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