What is turmeric?
Turmeric has a long history of medicinal use, especially for treatment of inflammatory conditions including osteoarthritis. [19]
Whether taken as a supplement or from food, curcumin, the active ingredient in turmeric, is very hard for the body to absorb.
Webber Naturals Advanced Turmeric features Meriva® a patented curcumin complex that has been clinically shown to significantly increase the absorption of curcumin. Clinical studies have also shown that Meriva curcumin supports a healthy inflammation response, joint mobility and flexibility, and also provides potent antioxidant activity. [1, 3, 11, 16, 30]
Key Ingredient: Meriva®
After 90 days of using Meriva patients reported:
Added Benefits of Meriva:
- Decreased key measures for exercise-related pain, stiffness and physical function. [1, 2]
- Social and emotional index (SEI) score resulted in a greater than 3-fold improvement. [1, 2]
- C-Reactive Protein (CRP) level, an inflammatory marker, decreased by 16-fold. [1, 2]
- Healthy blood vessel function support. [14]
- Reduced muscle soreness from oxidative stress and inflammation after exercise. [16]
Published Studies
Meriva® is supported by 38 clinical trials confirming its safety and efficacy.
1. Belcaro G, et al. Efficacy and safety of Meriva®, a curcumin-phosphatidylcholine complex, during extended administration in osteoarthritis patients. Altern Med Rev. 2010; 15(4): p. 337-44.
2. Belcaro G, et al. Product-evaluation registry of Meriva®, a curcumin-phosphatidylcholine complex, for the complementary management of osteoarthritis. Panminerva Med. 2010; 52 (2 Suppl 1): p. 55-62.
3. Belcaro G, et al. Meriva(R)+Glucosamine versus Condroitin+Glucosamine in patients with knee osteoarthritis: an observational study. Eur Rev Med Pharmacol Sci. 2014; 18(24): p. 3959-63.
4. Dugall M, et al. Effects of a curcumin-based supplementation in asymptomatic subjects with low bone density: a preliminary 24-week supplement study. European Review for Medical and Pharmacological Sciences. 2017; 21: 1684:1689.
5. Allegri P, Mastromarino A & Neri P, Management of chronic anterior uveitis relapses: efficacy of oral phospholipidic curcumin treatment. Long-term follow-up. Clin Ophthalmol. 2010; 4: p. 1201-6.
6. Mazzolani F. Pilot study of oral administration of a curcumin-phospholipid formulation for treatment of central serous chorioretinopathy. Clin Ophthalmol. 2012; 6: p. 801-6.
7. Mazzolani, F. & S. Togni, Oral administration of a curcumin-phospholipid delivery system for the treatment of central serous chorioretinopathy: a 12-month follow-up study. Clin Ophthalmol. 2013; 7: p. 939-45.
8. Mazzolani, F. & S. Togni, et al. The role of a novel oral curcumin delivery form (Meriva®) supplementation in meibomian gland dysfunction. Minerva Oftalmol. 2016; 58: p 1-5.
9. Kayabasi U, et al. Retinal examination for the diagnosis of Alzheimer’s Disease. Int J Ophthalm Clin Res. 2014; 1:002.10. Ledda A, et al. Meriva®, a lecithinized curcumin delivery system, in the control of benign prostatic hyperplasia: a pilot, product evaluation registry study. Panminerva Med. 2012; 54(1 Suppl 4): p. 17-22.
11. Di Pierro F. et al. Comparative evaluation of the pain-relieving properties of a lecithinized formulation of curcumin (Meriva®), nimesulide, and acetaminophen. J Pain Res. 2013; 6, 201-205.
12. Di Pierro, F & Settembre R. Safety and efficacy of an add-on therapy with curcumin phytosome and piperine and/or lipoic acid in subjects with a diagnosis of peripheral neuropathy treated with dexibuprofen. J Pain Res. 2013; 6: p. 497-503.12
13. Pajardi G, et al. Clinical usefulness of oral supplementation with alpha-lipoic Acid, curcumin phytosome, and B-group vitamins in patients with carpal tunnel syndrome undergoing surgical treatment. Evid Based Complement Alternat Med. 2014; 2014: p. 891310.
14. Appendino G, et al. Potential role of curcumin phytosome (Meriva) in controlling the evolution of diabetic microangiopathy. A pilot study. Panminerva Med. 2011; 53(3 Suppl 1): p. 43-9.
15. Steigerwalt R, et al. Meriva(R), a lecithinized curcumin delivery system, in diabetic microangiopathy and retinopathy. Panminerva Med. 2012; 54(1 Suppl 4): p. 11-6.
16. Drobnic F, et al. Reduction of delayed onset muscle soreness by a novel curcumin delivery system (Meriva®): a randomised, placebo-controlled trial. J Int Soc Sports Nutr. 2014; 11: p. 31.
17. Sciberras JN, et al. The effect of turmeric (Curcumin) supplementation on cytokine and inflammatory marker responses following 2 hours of endurance cycling. J Int Soc Sports Nutr. 2015; 12(1): p. 5.
18. Serpe R. Curcuma longa extract is effective in reducing blood levels of reactive oxygen species (ROS) and increasing antioxidant enzyme Glutathione peroxidase (GPx) in patients with cancer-related cachexia and oxidative stress. 6th Cachexia Conference Milan, Italy. December 8-10, 2011.
19. Belcaro G, et al. A controlled study of a lecithinized delivery system of curcumin (Meriva®) to alleviate the adverse effects of cancer treatment. Phytother Res. 2014; 28(3): p. 444-50.
20. Panahi Y, et al. Adjuvant therapy with bioavailability-boosted curcuminoids suppresses systemic inflammation and improves quality of life in patients with solid tumors: a randomized double-blind placebo-controlled trial. Phytother Res. 2014; 28(10): p. 1461-7.
21. Panhai Y, et al. Antioxidant effects of bioavailability-enhanced curcuminoids in patients with solid tumors: A randomized double-blind placebo-controlled trial. J Functional Food. 2014; (6) 615-622.
22. Golombick T, et al. The effect of curcumin (as Meriva) on absolute lymphocyte count (ALC), NK cells and T cell populations in patients with stage 0/1 chronic lymphocytic leukemia. Journal of Cancer Therapy. 2015; 6 (7):566-571.
23. Soldà C. et al., A case of locally advanced pancreatic cancer successfully resected after 14 months therapy with gemcitabine and Meriva®. International Journal of Pharmacology, Phytochemistry and Ethnomedicine. Vol 2, 2017.
24. Maccio A, Gramignano G & Madeddu C. Surprising results of a supportive integrated therapy in myelofibrosis. Nutrition. 2015; 31(1): p. 239-43.
25. Antiga A, et al. Oral Curcumin (Meriva) Is Effective as an Adjuvant Treatment and Is Able to Reduce IL-22 Serum Levels in Patients with Psoriasis vulgaris. BioMed Research International. vol. 2015, Article ID 283634.
26. Franceschi F. et al. A novel phospholipid delivery system of curcumin (Meriva®) preserves muscular mass in healthy aging subjects. European Review for Medical and Pharmacological Sciences. 2016; 20: 762-766.
27. Panahi, Y. et al. Curcumin lowers serum lipids and uric acid in subjects with nonalcoholic fatty liver disease: a randomized controlled trial. J Cardiovasc Pharmacol. 2016; 68: 223-229.
28. Panahi Y et al. Efficacy and Safety of Phytosomal Curcumin in Non-Alcoholic Fatty Liver Disease: A Randomized Controlled Trial. Drug Res (Stuttg). 2017 Apr; 67(4): 244-251.
29. Tenero L. et al. Antioxidant supplementation and exhaled nitric oxide in children with asthma. Allergy Asthma Proc. 2016; 37:e8-e13.
30. Rohith N. Thota, et al., Curcumin alleviates postprandial glycaemic response in healthy subjects: A cross-over, randomized controlled study. Scientific Reports, 2018 8:13679
31. Jessica J.A. Ferguson, Elizabeth Stojanovski, Lesley MacDonald-Wicks, Manohar L. Garg , Curcumin potentiates cholesterol-lowering effects of phytosterols in hypercholesterolaemic individuals. A randomised controlled trial. Ymeta(2017), https://doi.org/
32. Mazzolani, F. and S. Togni, Oral administration of a curcumin-phospholipid formulation (Meriva®) for treatment of chronic diabetic macular edema: a pilot study. Eur Rev Med Pharmacol Sci, 2018. (22):
33. Belcaro, G., et al., Interaction study between antiplatelet agents, anticoagulants, thyroid replacement therapy and a bioavailable formulation of curcumin (Meriva®) Eur Rev Med Pharmacol Sci, 2018. (22): 5042-5046
34. Di Pierro, F. and Zacconi P., et al., A naturally-inspired, curcumin-based lecithin formulation (Meriva® formulated as the finished product Algocur®) alleviates the osteo-muscular pain conditions in rugby players. Eur Rev Med Pharmacol Sci, 2017. (21): 4935-4940
35. Szymanski, M., et al., Short term dietary curcumin supplementation reduces gastrointestinal barrier damage and physiological strain responses during exertional heat stress. PresS. J Appl Physiol (September 21, 2017). doi:10.1152/japplphysiol.00515.2017
36. Ledda A, Belcaro G., et al., Temporary Kidney Dysfunction (TKD): Supplementation with Meriva® in Initial, Transient Kidney Micro-Macro Albuminuria, Panminerva Medica 2018 Nov 27
37. Marczylo TH, et al., Comparison of systemic availability of curcumin with that of curcumin formulated with phosphatidylcholine. Cancer Chemother Pharmacol. 2007; 60(2): p. 171-7.
38. Cuomo J, et al. Comparative absorption of a standardized curcuminoid mixture and its lecithin formulation. J Nat Prod. 2011; 74(4): p. 664-9.
2. Belcaro G, et al. Product-evaluation registry of Meriva®, a curcumin-phosphatidylcholine complex, for the complementary management of osteoarthritis. Panminerva Med. 2010; 52 (2 Suppl 1): p. 55-62.
3. Belcaro G, et al. Meriva(R)+Glucosamine versus Condroitin+Glucosamine in patients with knee osteoarthritis: an observational study. Eur Rev Med Pharmacol Sci. 2014; 18(24): p. 3959-63.
4. Dugall M, et al. Effects of a curcumin-based supplementation in asymptomatic subjects with low bone density: a preliminary 24-week supplement study. European Review for Medical and Pharmacological Sciences. 2017; 21: 1684:1689.
5. Allegri P, Mastromarino A & Neri P, Management of chronic anterior uveitis relapses: efficacy of oral phospholipidic curcumin treatment. Long-term follow-up. Clin Ophthalmol. 2010; 4: p. 1201-6.
6. Mazzolani F. Pilot study of oral administration of a curcumin-phospholipid formulation for treatment of central serous chorioretinopathy. Clin Ophthalmol. 2012; 6: p. 801-6.
7. Mazzolani, F. & S. Togni, Oral administration of a curcumin-phospholipid delivery system for the treatment of central serous chorioretinopathy: a 12-month follow-up study. Clin Ophthalmol. 2013; 7: p. 939-45.
8. Mazzolani, F. & S. Togni, et al. The role of a novel oral curcumin delivery form (Meriva®) supplementation in meibomian gland dysfunction. Minerva Oftalmol. 2016; 58: p 1-5.
9. Kayabasi U, et al. Retinal examination for the diagnosis of Alzheimer’s Disease. Int J Ophthalm Clin Res. 2014; 1:002.10. Ledda A, et al. Meriva®, a lecithinized curcumin delivery system, in the control of benign prostatic hyperplasia: a pilot, product evaluation registry study. Panminerva Med. 2012; 54(1 Suppl 4): p. 17-22.
11. Di Pierro F. et al. Comparative evaluation of the pain-relieving properties of a lecithinized formulation of curcumin (Meriva®), nimesulide, and acetaminophen. J Pain Res. 2013; 6, 201-205.
12. Di Pierro, F & Settembre R. Safety and efficacy of an add-on therapy with curcumin phytosome and piperine and/or lipoic acid in subjects with a diagnosis of peripheral neuropathy treated with dexibuprofen. J Pain Res. 2013; 6: p. 497-503.12
13. Pajardi G, et al. Clinical usefulness of oral supplementation with alpha-lipoic Acid, curcumin phytosome, and B-group vitamins in patients with carpal tunnel syndrome undergoing surgical treatment. Evid Based Complement Alternat Med. 2014; 2014: p. 891310.
14. Appendino G, et al. Potential role of curcumin phytosome (Meriva) in controlling the evolution of diabetic microangiopathy. A pilot study. Panminerva Med. 2011; 53(3 Suppl 1): p. 43-9.
15. Steigerwalt R, et al. Meriva(R), a lecithinized curcumin delivery system, in diabetic microangiopathy and retinopathy. Panminerva Med. 2012; 54(1 Suppl 4): p. 11-6.
16. Drobnic F, et al. Reduction of delayed onset muscle soreness by a novel curcumin delivery system (Meriva®): a randomised, placebo-controlled trial. J Int Soc Sports Nutr. 2014; 11: p. 31.
17. Sciberras JN, et al. The effect of turmeric (Curcumin) supplementation on cytokine and inflammatory marker responses following 2 hours of endurance cycling. J Int Soc Sports Nutr. 2015; 12(1): p. 5.
18. Serpe R. Curcuma longa extract is effective in reducing blood levels of reactive oxygen species (ROS) and increasing antioxidant enzyme Glutathione peroxidase (GPx) in patients with cancer-related cachexia and oxidative stress. 6th Cachexia Conference Milan, Italy. December 8-10, 2011.
19. Belcaro G, et al. A controlled study of a lecithinized delivery system of curcumin (Meriva®) to alleviate the adverse effects of cancer treatment. Phytother Res. 2014; 28(3): p. 444-50.
20. Panahi Y, et al. Adjuvant therapy with bioavailability-boosted curcuminoids suppresses systemic inflammation and improves quality of life in patients with solid tumors: a randomized double-blind placebo-controlled trial. Phytother Res. 2014; 28(10): p. 1461-7.
21. Panhai Y, et al. Antioxidant effects of bioavailability-enhanced curcuminoids in patients with solid tumors: A randomized double-blind placebo-controlled trial. J Functional Food. 2014; (6) 615-622.
22. Golombick T, et al. The effect of curcumin (as Meriva) on absolute lymphocyte count (ALC), NK cells and T cell populations in patients with stage 0/1 chronic lymphocytic leukemia. Journal of Cancer Therapy. 2015; 6 (7):566-571.
23. Soldà C. et al., A case of locally advanced pancreatic cancer successfully resected after 14 months therapy with gemcitabine and Meriva®. International Journal of Pharmacology, Phytochemistry and Ethnomedicine. Vol 2, 2017.
24. Maccio A, Gramignano G & Madeddu C. Surprising results of a supportive integrated therapy in myelofibrosis. Nutrition. 2015; 31(1): p. 239-43.
25. Antiga A, et al. Oral Curcumin (Meriva) Is Effective as an Adjuvant Treatment and Is Able to Reduce IL-22 Serum Levels in Patients with Psoriasis vulgaris. BioMed Research International. vol. 2015, Article ID 283634.
26. Franceschi F. et al. A novel phospholipid delivery system of curcumin (Meriva®) preserves muscular mass in healthy aging subjects. European Review for Medical and Pharmacological Sciences. 2016; 20: 762-766.
27. Panahi, Y. et al. Curcumin lowers serum lipids and uric acid in subjects with nonalcoholic fatty liver disease: a randomized controlled trial. J Cardiovasc Pharmacol. 2016; 68: 223-229.
28. Panahi Y et al. Efficacy and Safety of Phytosomal Curcumin in Non-Alcoholic Fatty Liver Disease: A Randomized Controlled Trial. Drug Res (Stuttg). 2017 Apr; 67(4): 244-251.
29. Tenero L. et al. Antioxidant supplementation and exhaled nitric oxide in children with asthma. Allergy Asthma Proc. 2016; 37:e8-e13.
30. Rohith N. Thota, et al., Curcumin alleviates postprandial glycaemic response in healthy subjects: A cross-over, randomized controlled study. Scientific Reports, 2018 8:13679
31. Jessica J.A. Ferguson, Elizabeth Stojanovski, Lesley MacDonald-Wicks, Manohar L. Garg , Curcumin potentiates cholesterol-lowering effects of phytosterols in hypercholesterolaemic individuals. A randomised controlled trial. Ymeta(2017), https://doi.org/
32. Mazzolani, F. and S. Togni, Oral administration of a curcumin-phospholipid formulation (Meriva®) for treatment of chronic diabetic macular edema: a pilot study. Eur Rev Med Pharmacol Sci, 2018. (22):
33. Belcaro, G., et al., Interaction study between antiplatelet agents, anticoagulants, thyroid replacement therapy and a bioavailable formulation of curcumin (Meriva®) Eur Rev Med Pharmacol Sci, 2018. (22): 5042-5046
34. Di Pierro, F. and Zacconi P., et al., A naturally-inspired, curcumin-based lecithin formulation (Meriva® formulated as the finished product Algocur®) alleviates the osteo-muscular pain conditions in rugby players. Eur Rev Med Pharmacol Sci, 2017. (21): 4935-4940
35. Szymanski, M., et al., Short term dietary curcumin supplementation reduces gastrointestinal barrier damage and physiological strain responses during exertional heat stress. PresS. J Appl Physiol (September 21, 2017). doi:10.1152/japplphysiol.00515.2017
36. Ledda A, Belcaro G., et al., Temporary Kidney Dysfunction (TKD): Supplementation with Meriva® in Initial, Transient Kidney Micro-Macro Albuminuria, Panminerva Medica 2018 Nov 27
37. Marczylo TH, et al., Comparison of systemic availability of curcumin with that of curcumin formulated with phosphatidylcholine. Cancer Chemother Pharmacol. 2007; 60(2): p. 171-7.
38. Cuomo J, et al. Comparative absorption of a standardized curcuminoid mixture and its lecithin formulation. J Nat Prod. 2011; 74(4): p. 664-9.
The preceding information is provided for educational purposes only. Consult a physician prior to use if you are pregnant, have gallstones or a bile duct obstruction, have stomach ulcers or excess stomach acid or are taking antiplatelet medications or blood thinners. Consult a physician if symptoms persist or worsen. Keep out of reach of children.