All uses except jet lag: Consult your physician if sleeplessness persists for more than 4 weeks (chronic insomnia). All uses: Avoid taking with alcohol or products that increase drowsiness. Consult a physician prior to use if you have cardiovascular, immune, liver, or chronic kidney disease, hormonal or seizure disorders, asthma, depression, diabetes, low blood sugar, or migraine. Consult a physician prior to use if you are taking steroids or blood thinners, medications for seizure or blood pressure, or medications to suppress the immune system (immunosuppressive medications), to affect mental state, or to increase sedation. Do not use this product if you are pregnant or breastfeeding. Stop use if allergy occurs or if you experience headache, confusion, or nausea. Keep out of reach of children.