Consult a physician prior to use: 1) if you have diabetes mellitus in which blood sugar is difficult to regulate, 2) if you are taking medications which inhibit peristaltic movement (e.g., opioids, loperamide), 3) if you have symptoms such as severe abdominal pain, nausea, vomiting, or fever (as these could be signs of abdominal constipation, disease of the oesophagus or the superior opening of the stomach (cardia), paralysis of the intestine, megacolon, fecal impaction, inflamed bowel, or appendicitis), 4) if you have bloody diarrhea, or 5) if you are pregnant or breastfeeding. Consult a physician if symptoms persist or worsen, or if laxative effect does not occur within seven days. Stop use and consult a physician if symptoms of digestive upset (e.g., diarrhea) occur, worsen, or persist beyond 3 days. Do not use if you are experiencing a sudden change in bowel habits that has persisted for more than 2 weeks, undiagnosed rectal bleeding, or failure to defecate following the use of another laxative product, or if you have an immunecompromised condition (e.g., AIDS, lymphoma, patients undergoing long-term corticosteroid treatment). Keep out of reach of children.