Consult a physician prior to use if you have diabetes mellitus in which blood sugar is difficult to regulate, are taking medications which inhibit peristaltic movement (e.g., opioids, loperamide), have symptoms such as abdominal pain, nausea, vomiting, or fever (as these could be signs of other serious conditions), are pregnant or breastfeeding, or are experiencing a sudden change in bowel habits that has persisted for more than 2 weeks, undiagnosed rectal bleeding, or failure to defecate following the use of another laxative product. Consult a physician if symptoms persist or worsen or if laxative effect does not occur within 7 days. Keep out of reach of children.